://module2 The WHO method page 6/9
WHO Ladder: Step 1 <<previous next>>
A useful first line of treatment is often the use of simple analgesics and NSAIDs. The table below shows a list of typical dosages.
| Drug | Dosage | Frequency | Route |
| Paracetamol | 500mg - 1g | 6 hourly | PO, PR |
| Ibuprofen | 400mg - 800mg | 8 hourly | PO |
| Diclofenac | 50mg | 8 hourly | PO |
| Diclofenac | 100mg | 18 hourly | PR |
| Ketoprofen | 50mg | 8 hourly | PO |
PO = oral, PR = rectal
When prescribing NSAIDs, it is important to check for any history of Asthma (can be exacerbated by NSAIDS), previous hypersensitivity reaction to ANY NSAID (class effect contraindicates use of any other NSAID), and active bleeding / ulceration. In all cases when NSAIDs will be used for a prolonged period, a gastroprotective drug should be prescribed eg. Lansoprazole 15mg od.
So a patient on step 1 may be on a drug regime like this:
Paracetamol 1g four times a day
Diclofenac 50mg three times a day
Lansoprazole 15mg a day