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Syringe driver prescription

The exact method of prescribing drugs via a syringe driver will differ depending on where you are working.  Please check locally for precise details.  The following is just a basic guide to key points of note.  The route can be given as either "continuous subcutaneous infusion", "subcutaneously via syringe driver".  To avoid ambiguity, it is preferable to clarify as follows:

Drug
Dose
Route
Frequency
Notes
Diamorphine 40mg CSCI via SD 24 hourly
Midazolam 10mg CSCI via SD 24 hourly

CSCI = Continuous SubCutaneous Infusion    SD = Syringe Driver

In patients whose pain is unstable, it is often preferable to prescribe a dose range rather than a single dose.  It is important to make sure that all responsible health care workers are aware that they may move up or down within this range according to the patient's needs.  An example is given below:

Drug
Dose
Route
Frequency
Notes
Diamorphine 60mg-90mg CSCI via SD 24 hourly
Midazolam 10-20mg CSCI via SD 24 hourly increase if severely agitated

It is important to ensure that an adequate breakthrough dose of analgesia is also prescribed.  The principle is still the same - the breakthrough dose should be a range equivalent to the four hourly dose equivalent.  In this case, this would be 10mg - 15mg of subcutaneous diamorphine.  

We will now look at commonly used drugs and drug combinations for the syringe driver.  

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Last updated September 2004